Following what names a company trademarks is a good way of predicting future releases. If Microsoft’s recent actions are anything to go by they’ve got something brewing, something big.
Among games rated for Australia and Brazil was the mysterious title “Fusion: Genesis”, and whatever it’s going to be all signs indicate a series. The database, searchable here, lists 3 titles featuring the “Fusion” name, namely: “Fusion: Genesis”, “Fusion Vault” and “Fusion Sentient”.
Microsoft seems to have some tricks up it’s sleeve, of particular note is “Fusion Sentient”, the use of the word Sentient could be a hint at something truly unique.